① Microarray chips
For Allergy diagnosis: specific IgE detection kit DropScreen® ST-1
(Manufacture and sale: Nippon Chemiphar Co., Ltd.)
Pipelines
Field | Chip content | Analytes | Applications |
Medicine | Allergens | IgEs | Allergy |
Virus proteins | IgGs, IgMs | Infection diseases | |
Autoantigens | IgGs | Autoimmune diseases | |
Antibodies | Biomarkers | Cancer, Dementia | |
Healthcare/Cosmetics | Antibodies | Biomarkers | |
Food | Antibodies | Allergens | |
Environment | Antibodies | Pollutants |
② Build-to-order manufacturing and collaboration
R-Nanobio prepares original biochips according to orders
③ Automatic instrument
We have developed “MP microarray analyzer”. Load the microarray chip and the predetermined reagent cartridge into the analyzer, press the start button on the panel for fully automated measurements. The test data is displayed and printed on the panel. The measurement time is 10-30 minutes.
④ Non-specific interaction- suppressive or biologically active surfaces by surface treatment
We provide some surface treatment technologies for suppression of non-specific interactions or cell adhesive. Cell growth enhancement is also enabled by the surface treatment.
Functionality | products | Photo-reactivity(wavelength for photo-irradiation) | ||
< 300 nm | < 360 nm | |||
Suppression of non-specific binding | Polyethylene glycol | 〇 | 〇 | |
Zwitter ion | Sulfobetaine | 〇 | 〇 | |
Phosphobetaine | 〇 | 〇 | ||
Carbobetaine | 〇 | 〇 | ||
Cell adhesive | gelatin | 〇 | 〇 |
⑤ Drug discovery from library composed of low molecular weight compounds-random sequence of peptide conjugates
The molecular evolution engineering developed by RIKEN has produced various functional peptide aptamers. Here peptides assisted activity and selectivity of low molecular weight drugs are aimed. Repositioning of low molecular weight drugs, replacement of antibody, middle molecular weight of drugs, and solid-phase synthesis will be enabled.